Pharmaceutico-Analytical Study and Clinical Evaluation of Tiktadi Ghrita Ointment in Kikkisa with special reference to Striae Gravidarum: A Randomized Controlled Trial
Abstract
Introduction: Striae gravidarum are formed with extensive stretching and rupture of elastic fibers present in dermis during pregnancy. The prevalence rate of striae gravidarum, varies from 50% to 90% in various studies among pregnant women. Tiktadi Ghrita, a formulation described in Yogaratnakar (Uttarkhand), aids in the treatment of Vrana, promoting wound healing and alleviating skin discoloration. This study aimed to find the effect of this new topical treatment option i.e., Tiktadi Ghrita ointment on Kikkisa in relation to striae gravidarum.
Aim and Objectives: To evaluate the pharmaceutico-analytical study and clinical effect of Tiktadi Ghrita Ointment in Kikkisa with special reference to Striae gravidarum.
Materials and Methods: Tiktadi Ghrita ointment will be prepared as per classical reference. The prepared formulation will be assessed with organoleptic characters and physicochemical parameters. comparative clinical study will be carried out in 2 groups where each group will receive respective drug and will be evaluated for their results on Kikkisa.
Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The result of clinical study will be drawn from the mentioned assessment criteria. Statistical analysis will be done accordingly.
Discussion: If significant positive results are obtained in this work, then it will be a valuable contribution and evidence that the drug Tiktadi Ghrita ointment is equally effective in Striae gravidarum as Karveer Taila.
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