Study Protocol for Pharmaceutico-Analytical study and Clinical Evaluation of modified cream form of Sahachara Ghrita on Mukhdushika with special reference to Acne Vulgaris: A Randomized Controlled Trial
Abstract
Background: Mukhadushika/Acne vulgaris is a common chronic inflammatory condition of the skin. It is a prevalent issue affecting approximately 80% of teenagers and young adults.[1] Sahachara Ghrita is mentioned in Bhaishajyaratnavali for Mukhadushika.[2] To address the challenges of applying Sahachara Ghrita, a cream formulation is being developed for easier and more convenient application.[3]
Aim: To evaluate the pharmaceutico-Analytical study and clinical effect of modified cream form of Sahachara Ghrita on Mukhdushika with special reference to Acne vulgaris.
Materials & Methods: Sahachara Ghrita will be prepared as per classical reference. Modified cream form Sahachara Ghrita will be prepared as per texts. The prepared formulation will be assessed with organoleptic characters and physicochemical parameters. Clinical study will be carried out in 2 groups with modified cream form of Sahachara Ghrita and standard drug Shalmali Kantakadi Lepa respectively. They will be evaluated for their results on Mukhadushika.
Result: The analytical parameters will be assessed to establish pharmaceutical standardization. The result of clinical study will be drawn from the mentioned assessment criteria. Statistical analysis will be done accordingly.
Conclusion: If significant positive results are obtained in this work, then it will be a valuable contribution and evidence that the drug modified cream form Sahachara Ghrita is effective in Mukhadushika.
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References
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