A controlled clinical study to evaluate the efficacy of Janu Basti and Asthi Shrinkhala in management of Janusandhigata Vata w.s.r to Osteoarthritis

  • Dr. Rakesh Post Graduate Scholar, Department of Kayachikitsa, Sri Sri College of Ayurvedic Science and Research, Bengaluru, Karnataka, INDIA.
  • Dr. Gopala Krishna G Professor & HOD, Sri Sri College of Ayurvedic Science and Research, Bengaluru, Karnataka, INDIA.
  • Dr. Sowmyashree U.P Associate Professor, Sri Sri College of Ayurvedic Science and Research, Bengaluru, Karnataka, INDIA.
  • Dr. Umesh C. Professor, Department of Kayachikitsa, Sri Sri College of Ayurvedic Science and Research, Bengaluru, Karnataka, INDIA.
Keywords: Asthishrinkhala, Glucosamine sulfate, Janubasti, Osteoarthritis, Sandhigata Vata

Abstract

Background : Sandhigata Vata is characterized by Shoola (pain), Shopha (swelling) and restricted movement of affected joints. Osteoarthritis is characterized by inflammation of joints, marked by progressive cartilage damage as a result of age related degenerative change or trauma. Sandhigata Vata correlates with Osteoarthritis. Objectives - The present study was intended to evaluate and compare the efficacy of Asthishrinkhala (Trial drug) and Glucosamine sulfate (Control drug) in Janusandhigatavata w.s.r to Osteoarthritis. Materials and Method - 40 subjects diagnosed with Janusandhigatavata were randomly assigned into two equal groups comprising of 20 subjects each. Subjects of Group A received Janubasti with Mahavishagarbha Taila and Tab. Glucosamine sulfate 500mg 1 T.I.D after food and subjects of Group B received Janubasti with Mahavishagarbha Taila and Tab. Asthishrinkhala 500mg 1 T.I.D after food for a duration of 30 days. Observation and Results - In the present study, Asthishrinkhala and Glucosamine sulfate both were beneficial in reducing the symptoms of Janu Sandhigata Vata. On comparison between the groups, Glucosamine sulfate was more in beneficial in reducing the symptom of Janu Sandhigata Vata compared to Asthishrinkhala. However there was a statistically non significant result between groups, overall the subjects on glucosamine sulfate expressed greater benefit compared to Asthishrinkhala. Conclusion - Both the drugs were beneficial in managing the symptoms of Sandigatavata, but overall the subjects treated with glucosamine sulfate expressed greater benefits compared to subjects treated with Asthishrinkhala.

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References

Charaka, Charaka Samhita, Ayurveda Deepika commentary of Chakrapani edited by Acharya Trivikrama Yadava Sharma, Chaukambha surabharathi prakshana. 2004.p.186.

Siddharth N. Shah, API Text book of Medicine, 8th edition Mumbai: Association of physicians of India; 2008.p.27.

Krishnachandra chunekar, editior. Bhavaprakasha Nigahatu. Reprint Edition. Varanasi: Chaukhamba Bharathi Academy; 2015.p.403.

Eugene J. Kucharz, Volodymyr Kovalenko, SándorSzántó, Olivier Bruyère, Cyrus Cooper & JeanYves Reginster (2016) A review of glucosamine for knee osteoarthritis: why patented crystalline glucosamine sulfate should be differentiated from other glucosamine to maximize clinical outcomes, Current Medical Research and Opinion, 32:6, 997-1004, DOI:10.1185/03007995.2016.1154521

Jadavji T, editor. Sushrutha Samhihta of Sushrutha, Chikitsa Sthana. Ch. 4, Ver. 8. Reprint Edition, Varanasi: Chowkhambha Orientalia; 2014. p. 420.
How to Cite
Dr. Rakesh, Dr. Gopala Krishna G, Dr. Sowmyashree U.P, & Dr. Umesh C. (2020). A controlled clinical study to evaluate the efficacy of Janu Basti and Asthi Shrinkhala in management of Janusandhigata Vata w.s.r to Osteoarthritis. Journal of Ayurveda and Integrated Medical Sciences, 5(02), 8-13. Retrieved from http://www.jaims.in/jaims/article/view/857
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Original Article